Live birth and multiple birth rates in women under age 38 by elective single embryo transfer (ESET) versus double embryo transfer (DET) in United States IVF clinics

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Reducing twin pregnancy rates after IVF--elective single embryo transfer (eSET).

Multiple pregnancy is a major complication of IVF and is associated with increased maternal, fetal and neonatal morbidity. Elective single embryo transfer (eSET) during IVF, rather than the more standard transfer of two embryos (double embryo transfer or DET), has been shown to significantly reduce the multiple pregnancy rate associated with IVF, while maintaining acceptable pregnancy rates. Co...

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Elective single versus double embryo transfer: live birth outcome and patient acceptance in a prospective randomised trial.

The purpose of this study was to determine which strategy of embryo transfer has a better trade-off in live birth delivery rate versus multiple pregnancy considering patient acceptance: elective single embryo transfer (eSET) or elective double embryo transfer (eDET). In all, 199 women <38 years of age undergoing their first IVF treatment in a private centre were included in a prospective open-l...

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Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization.

BACKGROUND The risks of premature birth and perinatal death are increased after in vitro fertilization. These risks are mainly due to the high incidence of multiple births, which relates to the number of embryos transferred. METHODS We performed a randomized, multicenter trial to assess the equivalence of two approaches to in vitro fertilization with respect to the rates of pregnancy that res...

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Economic evaluations of single- versus double-embryo transfer in IVF.

Multiple pregnancies lead to complications and induce high costs. The most successful way to decrease multiple pregnancies in IVF is to transfer only one embryo, which might reduce the efficacy of treatment. The objective of this review is to determine which embryo-transfer policy is most cost-effective: elective single-embryo transfer (eSET) or double-embryo transfer (DET). Several databases w...

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eSET irrespective of the availability of a good-quality embryo in the first cycle only is not effective in reducing overall twin pregnancy rates.

INTRODUCTION In several clinics, elective single-embryo transfer (eSET) is applied in a selected group of patients based on age and the availability of a good-quality embryo. Whether or not eSET can be applied irrespective of the presence of a good-quality embryo in the first cycle, to further reduce the twin pregnancy rate, remains to be elucidated. METHODS In patients <38 years two transfer...

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ژورنال

عنوان ژورنال: Fertility and Sterility

سال: 2016

ISSN: 0015-0282

DOI: 10.1016/j.fertnstert.2016.07.301